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Comments or Questions Contact: Webmaster
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Ming Yang |  |
| Oklahoma State University | ||
 Associate
Professor, Department of Botany |
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| Address:
104 Life Sciences
East, OSU, Stillwater, OK 74078
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| Phone:
405-744-9508
Fax: 405-744-7074
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| Email:
ming.yang@okstate.edu |
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| URL:
http://botany.okstate.edu/faculty/Yang/yang.html |
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| Ph.D.,
Plant Biology, 1996, Ohio
State University |
Lab Photo | |
| Postdoctoral: Plant Molecular Genetics 1996-1998, Cold Spring Harbor Laboratory |
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| Research
Emphasis: Cell
cycle progression and cell morphogenesis in Arabidopsis
thaliana |
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| Related
Activities: Teaching
Plant Anatomy and Biological Microtechnique |
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| Research
Description: My research interests are in the areas of cell cycle progression and cell morphogenesis in Arabidopsis. Our recent findings are concerned with the roles of two proteins, the ARABIDOPSIS SKP1-LIKE1 (ASK1) and CYCLIN A1;2 (CYCA1;2), in male meiosis. We found that in microsporocytes ASK1 regulates a series of sequential events that include nucleolar migration, homologue synapsis, chromosomal protein dynamics, and homologue separation. We are currently investigating how ASK1 regulates these events. In the case of CYCA1;2, we found that it regulates the progression of both meiosis I and meiosis II even though its peak expression only occurs in the pachytene stage. Because each nuclear division in mitosis is coupled with a peak of expression of mitotic cyclins, our findings on CYCA1;2 suggest a different mode of action for mitotic cyclins in meiosis than in mitosis. We are further exploring additional molecular differences between the meiotic cell cycle and the mitotic cell cycle with the aim to build a unified model for cell cycle progression in both meiosis and mitosis. Moreover, we are investigating other cell morphogenic events during Arabidopsis development. |
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| Recent
Publications:
Wang Y, Yang M (2007) In silico identification of co-transcribed core cell cycle regulators and transcription factors in Arabidopsis. J Integrative Plant Biol 49(8):1253-1260. Vitha S, Yang M, Sack FD, Kiss JZ (2007) Gravitropism in the starch excess mutant of Arabidopsis thaliana. Am J Bot 94(4):590-598. Wu H, Mori A, Jiang X, Wang Y, Yang M (2006) The INDEHISCENT protein regulates unequal cell divisions in Arabidopsis fruit. Planta, Online First, DOI: 10.1007/s00425-006-0351-8. Wang Y, Yang M (2006) The ARABIDOPSIS SKP1-LIKE1 (ASK1) protein acts predominately from leptotene to pachytene and represses homologous recombination in male meiosis. Planta 223: 613-617. Wang Y, Magnard J-L, McCormick S, Yang M (2004) Progression through meiosis I and meiosis II in Arabidopsis anthers is regulated by an A-type cyclin predominately expressed in prophase I. Plant Physiol 136: 4127-4135. Wang Y, Wu H, Liang G, Yang M (2004) Defects in nucleolar migration and synapsis in male prophase I in the ask1-1 mutant of Arabidopsis. Sex Plant Reprod 16: 273-282. |
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| Selected
Additional Publications: Magnard J-L, Yang M, Chen Y-CS, Leary M, McCormick S (2001) The Arabidopsis gene Tardy Asynchronous Meiosis is required for the normal pace and synchrony of cell division during male meiosis. Plant Physiol 127: 1157-1166. Yang M, Ma H (2001) Male meiotic spindle lengths in normal and mutant Arabidopsis cells. Plant Physiol 126: 622-630. Yang M, Hu Y, Lodhi M, McCombie WR, Ma H (1999) The Arabidopsis SKP1-LIKE1 gene is essential for male meiosis and may control homologue separation. Proc Natl Acad Sci USA 96: 11416-11421. Yang
M, Nadeau JA, Zhao L, Sack FD (1999) Characterization of a cytokinesis
defective (cyd1) mutant of Arabidopsis. J Exp
Bot 50: 1437-1446. |
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